1) Resveratrol is Anti-Aging
Resveratrol is effective in inhibiting or reversing some of the effects of aging like osteoporosis, sarcopenia, mental processes decline, etc…
2) Resveratrol is Neuroprotective
Resveratrol appears to reduce seizures and hippocampal neurotoxicity in animal models (by suppressing kainate receptor signaling).
Resveratrol acts on glial cells which are involved in neurotransmission and it has been noted to increase glutamate uptake into glial cells.
Resveratrol induces the antioxidant enzyme, heme-oxygenase 1, which is linked to neuroprotection.
Lifelong supplementation of resveratrol may increase lifespan and delay bio markers of Alzheimer’s (by preventing beta-amyloid and tau protein aggregation).
Resveratrol increases IGF-1 in the memory center (hippocampus) of the brain, which improves memory.
3) Resveratrol Contributes to Heart Health
Resveratrol has been demonstrated to reduce blood pressure in people at risk for heart disease.
Resveratrol has been investigated for its contribution to heart health after a meta-analysis first found a significant risk reduction associated with 1-2 glasses (150-300 ml) of wine daily.
Resveratrol helps heart health by inhibiting NADPH (in vitro) and by inducing eNOS.
Resveratrol is anti-atherogenic (reduces the formation of plaque in arteries).
Resveratrol also attenuates Trimethylamine-N-Oxide (TMAO)-Induced atherosclerosis by regulating TMAO synthesis and bile acid metabolism via changing the gut microbiota.
4) Resveratrol Benefits Glucose Balance
Resveratrol has been shown to increase insulin sensitivity in obese people (150 mg daily) and therefore helps with glucose metabolism.
Resveratrol can be useful in preventing and treating diabetes.
5) Resveratrol Combats Obesity
Resveratrol can cause the death of fat cells.
Resveratrol can benefit weight loss by inhibiting fatty acid synthase, lipoprotein lipase and hormone-sensitive lipase.
Resveratrol enhances mitochondrial function (through SIRT1 activation of PGC 1alpha), which can improve metabolism.
6) Resveratrol Helps Bones
Resveratrol increases bone cells by redirecting stem cells from becoming fat cells, which may increase bone health.
Resveratrol synergizes with Vitamin D for bone health.
7) Resveratrol May Prevent Cancer
Resveratrol protects against liver cancer (in vitro) and is being investigated for usage in liver metastasis prevention in humans.
It has shown promise on skin cancers when used on the body surface of mice.
Resveratrol is effective against esophageal cancer when ingested orally in rats.
Resveratrol can be used to prevent and treat breast cancer.
Resveratrol’s anti-cancer effects come, in part, from its regulation of the topoisomerase II enzyme.
Resveratrol inhibits the growth of Leukemia cells.
8) Resveratrol Helps With Liver Health
In animal models, resveratrol can help conditions in which bile flow is obstructed by inhibiting MMP-2 and MMP-9.
Resveratrol prevents and improves Nonalcoholic Fatty liver disease (NAFLD).
It prevents liver damage in sepsis.
9) Resveratrol Helps Muscle Growth
Resveratrol has positive effect on muscle growth.
Resveratrol supplementation enhances aerobic performance.
10) Resveratrol Protects Against Radiation
Resveratrol has a good anti-radiation effect (at 100 and 300 mg/Kg concentration).
11) Resveratrol Prevents Hearing Loss
Resveratrol has a protective effect on noise-induced hearing loss.
Resveratrol also prevents toxicity of ear caused by cisplatin (a chemotherapeutic agent used to treat cancer).
12) Resveratrol Increase Sex Hormones
High doses of Resveratrol can increase Testosterone.
Resveratrol could act as an Estrogen agonist or Estrogen antagonist.
13) Resveratrol Induces Autophagy
Consumption of resveratrol may be connected to autophagy induction.
14) Resveratrol for Acne Treatment
Resveratrol gel showed positive results in treatment of Acne in humans.
15) Resveratrol Helps Fight Infections
Antiviral activity of Resveratrol
Resveratrol inhibited herpes virus infection of ducks, geese etc.
Resveratrol inhibited the Influenza virus.
Resveratrol has shown to inhibit the activity of Epstein-Barr virus.
Resveratrol has shown to inhibit Herpes simplex virus-1 and Herpes simplex virus-2 (HSV-1 and HSV-2).
Resveratrol has shown to inhibit the Respiratory Syncytial virus in mice.
Resveratrol showed activity against Human Immunodeficiency virus-1 and was synergistic with decitabine.
Resveratrol also inhibited Varicella zoster and Enterovirus 71 (EV 71).
Resveratrol inhibited African swine fever virus in-vitro.
Resveratrol with quercetin showed an inhibitory effect on Human meta pneumonia (hMPV) virus infection.
Resveratrol inhibited Human rhinovirus (HRV) and Cytomegalovirus.
Anti-fungal activity of Resveratrol
Resveratrol showed anti-fungal activity against Candida albicans.
Antibacterial activity of Resveratrol
Resveratrol showed antibacterial activity against MRSA in humans (Methicillin Resistant Staphylococcus aureus).
Resveratrol showed antibacterial activity against E.Coli.
Resveratrol inhibited the growth of Propionibacterium acnes, the bacteria which causes acne.
Resveratrol had an antibacterial effect on Haemophilus ducreyi.
Resveratrol inhibited Arcobacter butzleri and Arcobacter cryaerophilusa.
16) Resveratrol Increases Sensitivity to Vitamin D
Resveratrol and SIRT1 make you more sensitive to vitamin D – it potentiates the vitamin D receptor (VDR).
Resveratrol potentiates VDR by (1) potentiating 1,25D binding to VDR; (2) activating RXR; (3) stimulating SIRT1.
Other
Resveratrol decreases MAOA (strong), which should help with depression.
Resveratrol prevents a high-fat diet decrease in Tregs.
Resveratrol inhibits mTOR in a unique way, which should benefit autoimmunity, cancer, and longevity.
Resveratrol activates AMPK.
Source: www.selfhacked.com (Joe Cohen)
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